Contrast agent concentration measurements affecting quantification of bolus-tracking perfusion MRI
نویسندگان
چکیده
منابع مشابه
Quantification Issues in Bolus-Tracking Perfusion MRI
Bolus-tracking perfusion MRI is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly in the antecubital vein in the patients arm by means of an MR-compatible power injector. This bolus of contrast agent is pushed in the direction of the heart by means of a saline flush. Continuous dy...
متن کاملIs quantification of bolus tracking MRI reliable without deconvolution?
Bolus tracking data obtained with paramagnetic intravascular tracers are commonly analyzed and quantified by the direct measurement of properties of the tissue concentration-time curve (e.g., time to peak (TTP)). The measurement of these "summary parameters" is used as an accessible alternative approach to the complex deconvolution procedure, and provides indirect measures of perfusion. However...
متن کاملComputational Fluid Dynamics Simulations of Contrast Agent Bolus Dispersion in a Coronary Bifurcation: Impact on MRI-Based Quantification of Myocardial Perfusion
Contrast-enhanced first-pass magnetic resonance imaging (MRI) in combination with a tracer kinetic model, for example, MMID4, can be used to determine myocardial blood flow (MBF) and myocardial perfusion reserve (MPR). Typically, the arterial input function (AIF) required for this methodology is estimated from the left ventricle (LV). Dispersion of the contrast agent bolus might occur between t...
متن کاملCerebral perfusion imaging by bolus tracking.
Cerebral perfusion may be visualized by the dynamic imaging of an intravenously injected bolus (a few milliliters) of clinically approved gadolinium-containing contrast media. During its passage through the vasculature of the brain, the contrast agent induces magnetic field disturbances, which can be seen as signal loss on appropriately weighted dynamic MRI. This article deals with the quantita...
متن کاملA novel MRI contrast agent synthesized by ion exchange method
Objective: In this study, the zeolite-coated iron oxide nanoparticles were evaluated as MRI contrast agent and effect of the nanocomposite synthesis method on MRI contrast was tested. Materials and Methods: Ion exchange method was used for synthesis of iron oxide-zeolite and the as prepared nanocomposite was characterized by XRD, FESEM and TEM. The nanocomposite toxicity in the cell culture, a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2007
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.21362